I was originally going to make the title "Russell Watson: What You Got, Son?" but obviously, that would be stupid. So I decided not to mention it.
Ahem.
Anyway, today's post is (surprisingly) about international singing sensation and all-round famous guy Russell Watson. Ever heard of him? NOR HAD I.
But last year he popped up on an episode of Never Mind the Buzzcocks, which aired on the evening of the 2nd December. I had an important exam the next day, so obviously I was watching. Mr Watson mentioned that he had had a brain tumour. I, as yet undiagnosed,* thought nothing more of it, not least because the notorious buffoon Tim Westwood was hosting the show and I was quite busy despising him.
About a week later, I got the call from the hospital announcing that I had a pituitary adenoma. Russell Watson was far from my mind. But then one day, as I was waiting to collect a takeaway in my local Chinese, I began paging through their ancient and tattered copies of the Daily Mail** and came across a month-old article about the same Mr Watson and his second round of brain surgery for a "benign brain tumour".
So obviously I had to look it up. After a bit of searching, my suspicions were confirmed: Russell Watson's pituitary gland also enjoys cultivating adenomas in its spare time. I can't really say why knowing this made me feel better, but I guess it's just vaguely reassuring to know that there are other people out there. The poor guy had a particularly nasty case of the pituitary tumour as well, he's had two surgeries and radiotherapy, and the first surgery apparently had a knock-on effect to his pituitary function, something which so far I've been lucky enough to avoid.
However, I would like to take this opportunity to glower at the British press for their woeful lack of precision when reporting on brain tumours. It seems that any distinction beyond that of "benign" and "cancerous" is completely beyond them. For anyone who knows their oligodendroglioma from their meningioma, and particularly for anyone trying to identify famous fellow tumourheads, it makes life rather challenging. Are the details of a diagnosis too much to ask for?
Also, while I don't mean to sound like a stalker who's read every article on the subject, I have to say that I particularly empathised with the last lines from with Russell Watson in this article: "Specialists repeatedly told him that he was only suffering from stress, to which he replied: 'The only thing that's stressing me is this pain in my head.'"
Just like all the years of me visiting various doctors complaining that my hair was falling out. And my heart was doing funny things. And I felt tired all the time.***
UPDATE: You may also be interested in further posts I've made about famous people with pituitary adenomas, which you can find here and here, and there's also this post specifically looking at famous people with Cushing's Disease and another post looking at the strange shortage of famous women with acromegaly when compared to their male counterparts.
________________________________________________________________________
*Though admittedly in the realm of "we're pretty sure it's a pituitary adenoma. Because it's the only idea we have left".
** Oh god. I know. I'm so sorry. I'll never do it again.
***Any doctor treating me in future may be interested to know that if any symptom I may display is ever put down to "stress" again, I will not be held responsible for my actions. Of course, being accused of suffering from "stress" comes with the unfortunate Catch-22 that anyone repeatedly insisting that they're not bloody stressed looks exactly like a stressed-out mentalist. Le sigh.
Sunday, 13 November 2011
Saturday, 12 November 2011
Another gem from Terence
Following my earlier post today, I've stalked Terence Hale, who is certainly rather an opinionated chap, around the Guardian website. Interestingly, he signs his earlier comments as Dr Terence Hale but then becomes plain Terence Hale later. This is relevent in no way to pituitary adenomas, but I had to share it anyway.
I was intrigued to gain a small insight into the marriage of this mysterious character...
"Miss or Mrs Winfrey (if Mrs., poor man) makes her money by televised sermons to extravagant, don't wash-up or take the dog for a walk stuck to the television all day women like my wife."
And yet:
"In Switzerland most supermarkets have restaurants which usually means the wife go's shopping and the husband in the restaurant.
Regards Dr. Terence Hale"
Terry's Top Tips for Valentine's Day:
"1) Open the oven door
2) Block both ears
3) Play Jimmy Hendrix
4) Walk on water
5) Have a nervous break down
6) Find a duck pond that smells
7) Cut your self
Don't phone me, I'll phone you.
Regards Dr. Terence Hale"
His thoughts on the Royal Wedding:
"Just helpful advice for the Royal marriage. Usually people who get married are in love. This is where the problems starts. Love in like a piece of cheese, the first day nice and soft, the second day a little harder and the third day it smells terrible.
Regards Dr. Terence Hale"
And finally:
"Many people, including myself have reservations in disclosing close encounter with aliens because of being ridiculed.
It takes much courage to confide such an encounter.
Regards Dr. Terence Hale"
I was intrigued to gain a small insight into the marriage of this mysterious character...
"Miss or Mrs Winfrey (if Mrs., poor man) makes her money by televised sermons to extravagant, don't wash-up or take the dog for a walk stuck to the television all day women like my wife."
And yet:
"In Switzerland most supermarkets have restaurants which usually means the wife go's shopping and the husband in the restaurant.
Regards Dr. Terence Hale"
Terry's Top Tips for Valentine's Day:
"1) Open the oven door
2) Block both ears
3) Play Jimmy Hendrix
4) Walk on water
5) Have a nervous break down
6) Find a duck pond that smells
7) Cut your self
Don't phone me, I'll phone you.
Regards Dr. Terence Hale"
His thoughts on the Royal Wedding:
"Just helpful advice for the Royal marriage. Usually people who get married are in love. This is where the problems starts. Love in like a piece of cheese, the first day nice and soft, the second day a little harder and the third day it smells terrible.
Regards Dr. Terence Hale"
And finally:
"Many people, including myself have reservations in disclosing close encounter with aliens because of being ridiculed.
It takes much courage to confide such an encounter.
Regards Dr. Terence Hale"
IMFW: Pituitary Newsflash
I have to make a confession. I've been writing my Interesting Medical Fact of the Week posts in advance and lining them up to post automatically every week. Which is fine, until I read something new and exciting and physically cannot wait to post it, for fear of literally exploding with excitement.
And no-one wants to have to clean that up.
So as I was browsing for news of new medical marvels, I came across this article. For those of you incapable of clicking the link, I'll break it down for you: scientists in Japan have taken stem cells from mice embryos and successfully grown working pituitary tissue, which, when transplanted into mice with pituitary defects, began to produce some of the hormones that these mice were lacking.
EXCITING. Obviously a long long way from any kind of human treatment, but I'm sure there are plenty of folk out there who jumped for joy in the middle of their growth hormone injections at the vaguest prospect of such a thing.
Also an entertaining read is the comments section at the bottom of the article. One user rails against any money being spent on researching pituitary problems when more people die from malaria and AIDS and advises a Benthamite strategy for prioritising areas of medical research.* I also particularly like a comment by "Terence Hale" which states that:
"There are many endocrine glands in the body with the main ones being the pituitary gland, thyroid, thymus, adrenal glands, and the pancreas, but one often forget the Hypothalamus which links the nervous system to the endocrine system via the pituitary gland is “the captain of the ship”, a clock work. Putting things in between such as hormones or gland implants is “rocking the boat”. Hormone therapy has help many but has it's costs. The implant in such a clock work could present problems."
I think we all feel enlightened after that. I'm assuming that Terence's trouble expressing himself is down to Google Translate,** because a little bit of further research throws up another comment of his, giving a recipe suggestion in which he suggests taking a worm chicken embryo and placing it in an Irish Gnome Bowl before chopping it up with a Saudi Arabian execution sward.***
______________________________________________________________
*Of course, we could save even more money by just killing all the sick people. And thus prevent the spread of communicable diseases, too. Why has no-one thought of this before?
**When will those bastards get it right?
***Full recipe, because it is quite funny: "20 g of freshly cut wheat corns are socked in dulcolax juice and given to nearby chicken who has less than 5,000 fly hours. This produces a shelled embryo. The embryo is then take while worm and placed in saucepan. After exactly 3 min. the shelled embryo is taken from the saucepan with a teaspoon, coffee spoons are not suitable and placed in an Irish Gnome bowl. The embryo is prepared for eating by using a horizontal guillotine placed of the right side of the embryo and moved to the left side with the embryo in the middle. A Saudi Arabian execution sward may also be used."
And no-one wants to have to clean that up.
So as I was browsing for news of new medical marvels, I came across this article. For those of you incapable of clicking the link, I'll break it down for you: scientists in Japan have taken stem cells from mice embryos and successfully grown working pituitary tissue, which, when transplanted into mice with pituitary defects, began to produce some of the hormones that these mice were lacking.
EXCITING. Obviously a long long way from any kind of human treatment, but I'm sure there are plenty of folk out there who jumped for joy in the middle of their growth hormone injections at the vaguest prospect of such a thing.
Also an entertaining read is the comments section at the bottom of the article. One user rails against any money being spent on researching pituitary problems when more people die from malaria and AIDS and advises a Benthamite strategy for prioritising areas of medical research.* I also particularly like a comment by "Terence Hale" which states that:
"There are many endocrine glands in the body with the main ones being the pituitary gland, thyroid, thymus, adrenal glands, and the pancreas, but one often forget the Hypothalamus which links the nervous system to the endocrine system via the pituitary gland is “the captain of the ship”, a clock work. Putting things in between such as hormones or gland implants is “rocking the boat”. Hormone therapy has help many but has it's costs. The implant in such a clock work could present problems."
I think we all feel enlightened after that. I'm assuming that Terence's trouble expressing himself is down to Google Translate,** because a little bit of further research throws up another comment of his, giving a recipe suggestion in which he suggests taking a worm chicken embryo and placing it in an Irish Gnome Bowl before chopping it up with a Saudi Arabian execution sward.***
______________________________________________________________
*Of course, we could save even more money by just killing all the sick people. And thus prevent the spread of communicable diseases, too. Why has no-one thought of this before?
**When will those bastards get it right?
***Full recipe, because it is quite funny: "20 g of freshly cut wheat corns are socked in dulcolax juice and given to nearby chicken who has less than 5,000 fly hours. This produces a shelled embryo. The embryo is then take while worm and placed in saucepan. After exactly 3 min. the shelled embryo is taken from the saucepan with a teaspoon, coffee spoons are not suitable and placed in an Irish Gnome bowl. The embryo is prepared for eating by using a horizontal guillotine placed of the right side of the embryo and moved to the left side with the embryo in the middle. A Saudi Arabian execution sward may also be used."
Friday, 11 November 2011
My Head Revisited: First Trip to Hospital
I have set this post to appear online at precisely 11.11am on the 11/11/11. If I could define it down to the second, believe me I would. Because I am lame that way. Anyhow. On to the story...
***
In January 2010, a chain of events was set in motion which led to the first of my many trips to hospital and, incidentally, the first time I tried sushi. Of the two experiences, I preferred the latter. From what I've seen, hospital visits rarely come with a side of pickled ginger.
And I love pickled ginger.
Sadly I can no longer remember the date in question, but I think it was around the 18th January; I was back at university and, being a studious and dilligent character, I had spent the entire day sitting in my room reading books about Old English poetry. Consequently, I couldn't quite work out why, ever since I'd woken up, my heart had been beating as fast as though I'd just run for the bus.
At about four o'clock, I used the excellent online stopwatch to work out that my heartrate was around 140 beats per minute. So I decided to do what any sane individual would do when their local doctor's practice is a two-minute walk away. I called NHS Direct.
NHS Direct sent me to the doctors. Feeling like a bit of an idiot, I ambled into the reception, was immediately rushed in to see the nurse (ever wanted to skip the queue? Just develop heart problems!)* and found myself wired up to an EKG, which looked rather like some kind of creepy mechanical chest octopus. I sat there for a few minutes and the nurse agreed that yes, my heart was rather speedy. Then I was sent to a doctor, who took a look at the creepy mechanical chest octopus printout and agreed that yes, my heart was indeed rather speedy.
So the doctor sent me to the hospital. My very nice college booked and paid for the taxi to take me to A&E and I grabbed my very nice friend Cherry to accompany me.
"Heart problems" is one of those magical phrases that gets you rushed through A&E much faster than, say, a mere broken bone or accidental breadknife incident - although of course it does mean that, as an entirely healthy-looking young person, you're liable to get a few evils from the folk who've been waiting there, oozing gently, for an hour.
Once I went through to see a doctor, the fun really started. Immediate assumptions were that either:
1) I must be having a panic attack.
or
2) I must have taken some kind of exciting illicit substance.
I think that option 1 was rapidly discounted due to the carefree nonchalance with which I munched my way through a packet of McCoys** and giggled as the doctor on duty made me blow through a small tube and massage my neck in an attempt to get my heartrate down. Of course, no matter how many times I insisted that option 2 was not an option, they refused to believe me.
Eventually they admitted defeat and sent me deeper into the hospital, where I got a whole bed to myself. Yay! I had a smorgasbord of blood tests and was wired up to another heartrate monitor which, annoyingly, was set to beep frantically any time my heartrate went over 140bpm. As it spent the whole time hovering around the 140 mark, this quickly got extremely irritating.
Cherry kindly volunteered to read aloud my book of translated Old English poetry to me, which resulted in her learning quite a lot of new and exciting vocabulary, like "seraphim", "fetters", and "vassal". Quite inexplicably, she lost interest only partway through a poem.
I sat in the hospital, waiting for my blood test results to come back, until about 11 o'clock at night. The doctors weren't sure whether I'd have to stay overnight, and so Cherry, as well as looking after me very well, (although I can never forgive her lack of interest in Anglo-Saxon literature) also had the fun job of phoning my parents and boyfriend, to let them know what was going on.
Finally, late at night, having had no dinner, it was announced that all my blood tests had come back fine, they had no idea what the hell was wrong with me, and that I should go home. If my heartrate was still fast in the morning, I was told to go back to the doctors.
It was good to be able to phone my parents and reassure them that I was not on death's door, but attempting to go to sleep with a heartrate of 140 is virtually impossible, and I was not reassured when, the next day, the doctor incredulously asked me "they let you go home from hospital with a heartrate of 140 and no medication?", with a look of horror on his face.
But more of that at a later date...
UPDATE: Click here to read my next post about getting a diagnosis. Or click here to go back and read more about my initial symptoms.
________________________________________________________________________
*N.B. This doesn't work as well in the supermarket.
**Incidentally, I hadn't noticed until recently that McCoys advertise themselves as "man crisps". WTF. Seriously, are their marketing team like five years old? Wikipedia, my one true love, tells me that McCoys are, and I quote, 'promoted by United Biscuits*** "as the only overtly male-targeted crisp brand"'. Don't believe anyone would say something that stupid, let alone base an ad campaign around it? Here's the website.
***Words fail me.
***
In January 2010, a chain of events was set in motion which led to the first of my many trips to hospital and, incidentally, the first time I tried sushi. Of the two experiences, I preferred the latter. From what I've seen, hospital visits rarely come with a side of pickled ginger.
And I love pickled ginger.
Sadly I can no longer remember the date in question, but I think it was around the 18th January; I was back at university and, being a studious and dilligent character, I had spent the entire day sitting in my room reading books about Old English poetry. Consequently, I couldn't quite work out why, ever since I'd woken up, my heart had been beating as fast as though I'd just run for the bus.
At about four o'clock, I used the excellent online stopwatch to work out that my heartrate was around 140 beats per minute. So I decided to do what any sane individual would do when their local doctor's practice is a two-minute walk away. I called NHS Direct.
NHS Direct sent me to the doctors. Feeling like a bit of an idiot, I ambled into the reception, was immediately rushed in to see the nurse (ever wanted to skip the queue? Just develop heart problems!)* and found myself wired up to an EKG, which looked rather like some kind of creepy mechanical chest octopus. I sat there for a few minutes and the nurse agreed that yes, my heart was rather speedy. Then I was sent to a doctor, who took a look at the creepy mechanical chest octopus printout and agreed that yes, my heart was indeed rather speedy.
So the doctor sent me to the hospital. My very nice college booked and paid for the taxi to take me to A&E and I grabbed my very nice friend Cherry to accompany me.
"Heart problems" is one of those magical phrases that gets you rushed through A&E much faster than, say, a mere broken bone or accidental breadknife incident - although of course it does mean that, as an entirely healthy-looking young person, you're liable to get a few evils from the folk who've been waiting there, oozing gently, for an hour.
Once I went through to see a doctor, the fun really started. Immediate assumptions were that either:
1) I must be having a panic attack.
or
2) I must have taken some kind of exciting illicit substance.
I think that option 1 was rapidly discounted due to the carefree nonchalance with which I munched my way through a packet of McCoys** and giggled as the doctor on duty made me blow through a small tube and massage my neck in an attempt to get my heartrate down. Of course, no matter how many times I insisted that option 2 was not an option, they refused to believe me.
Eventually they admitted defeat and sent me deeper into the hospital, where I got a whole bed to myself. Yay! I had a smorgasbord of blood tests and was wired up to another heartrate monitor which, annoyingly, was set to beep frantically any time my heartrate went over 140bpm. As it spent the whole time hovering around the 140 mark, this quickly got extremely irritating.
Cherry kindly volunteered to read aloud my book of translated Old English poetry to me, which resulted in her learning quite a lot of new and exciting vocabulary, like "seraphim", "fetters", and "vassal". Quite inexplicably, she lost interest only partway through a poem.
I sat in the hospital, waiting for my blood test results to come back, until about 11 o'clock at night. The doctors weren't sure whether I'd have to stay overnight, and so Cherry, as well as looking after me very well, (although I can never forgive her lack of interest in Anglo-Saxon literature) also had the fun job of phoning my parents and boyfriend, to let them know what was going on.
Finally, late at night, having had no dinner, it was announced that all my blood tests had come back fine, they had no idea what the hell was wrong with me, and that I should go home. If my heartrate was still fast in the morning, I was told to go back to the doctors.
It was good to be able to phone my parents and reassure them that I was not on death's door, but attempting to go to sleep with a heartrate of 140 is virtually impossible, and I was not reassured when, the next day, the doctor incredulously asked me "they let you go home from hospital with a heartrate of 140 and no medication?", with a look of horror on his face.
But more of that at a later date...
UPDATE: Click here to read my next post about getting a diagnosis. Or click here to go back and read more about my initial symptoms.
________________________________________________________________________
*N.B. This doesn't work as well in the supermarket.
**Incidentally, I hadn't noticed until recently that McCoys advertise themselves as "man crisps". WTF. Seriously, are their marketing team like five years old? Wikipedia, my one true love, tells me that McCoys are, and I quote, 'promoted by United Biscuits*** "as the only overtly male-targeted crisp brand"'. Don't believe anyone would say something that stupid, let alone base an ad campaign around it? Here's the website.
***Words fail me.
Labels:
blood tests,
cherry,
doctors,
heart,
heartrate,
hospital,
NHS Direct,
poetry,
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Wednesday, 9 November 2011
Health, Wealth & Happiness
In the ladies bathroom* at my place of work, a minor change was recently wrought when the former hand-drier/paper towel dispenser combo were replaced by a single hi-tech hand drier, of the new variety which seem designed not merely to blow water off your hands, but to have a crack at taking the skin off as well.
It's highly efficient, no doubt, and proudly states that by using it, you are helping to reduce landfill and thereby save the world. But today, after walking to work in a downpour, I found myself reflecting on the fact that its highly-specialised hand-drying design has come at the cost of other convenient functions of the hand-driers of old: namely, drying off wet clothes and hair and warming you up a bit. Of course, you can still use the Air Force Sandstorm Erosion™ to dry your hair. Providing you don't mind being scalped in the process.
But anyway, it got me thinking about its designers, who were no doubt given a clear spec: make the best hand-dryer possible. And they did. And everyone was delighted. It probably wasn't until monsoon season rolled its way around to Dryer Towers** that someone thought: 'Hang on a minute - the old hand drier was far less exciting and high tech, but at least it could deal with waterlogged socks.'
And, in a really obscure and slightly convoluted fashion,*** health is kind of like that, in that you don't notice what you've got til it's gone - but even then, sometimes it can take a surprisingly long time to catch your attention. I went from someone who never, ever had a headache to someone who got them regularly, but the change was so insidious over several years that it never even occurred to me that maybe I should mention this to a doctor - even after my heart had made it blindingly obvious to all and sundry that there was Something Clearly Wrong. Yes, I am just smart that way.
Now, I find myself (thank everything) on the flip side of that because I am (thank everything again) currently slowly getting better. Yes, I'm still not quite right, my hair's still falling out and my heart gave a very brief but exciting display of acrobatics as I ate my pasta last night,**** but I am so much better than I was. And I'm still in that happy honeymoon zone of improved health, where every now and again I have to take a moment to appreciate the fact that I can run for a bus without hyperventilating, that I can dance for an hour without needing a sit-down, and that my bruising has improved to the point where most days I can wear a skirt with no tights and not look like a victim of domestic violence.
Obviously the hope that I'm hoping ever so fervently is that I'm fixed and will continue to be fixed and, bar the odd MRI and pituitary-adenoma-related chat (for old times sake) I will darken my local hospital's doorstep much less frequently. I don't know if that will happen. But, although no doubt we'll all get used to the new hand dryer in time, I hope that - for as long as this improvement lasts - I don't lose my appreciation for feeling healthy :D
___________________________________________________________________________
* I say bathroom. I mean toilets. There is no bath in there. Because that would be weird.
**Just to clarify, I am making this up.
***Or, if you live in my head, a really obvious and straightforward one.
****Because the pasta was just that good. Incidentally, another side effect of this illness has been that I've completely lost all ability to appreciate lines in songs like "my heart skips a beat". I just hear them and think: Quick! To the cardiologist!
It's highly efficient, no doubt, and proudly states that by using it, you are helping to reduce landfill and thereby save the world. But today, after walking to work in a downpour, I found myself reflecting on the fact that its highly-specialised hand-drying design has come at the cost of other convenient functions of the hand-driers of old: namely, drying off wet clothes and hair and warming you up a bit. Of course, you can still use the Air Force Sandstorm Erosion™ to dry your hair. Providing you don't mind being scalped in the process.
But anyway, it got me thinking about its designers, who were no doubt given a clear spec: make the best hand-dryer possible. And they did. And everyone was delighted. It probably wasn't until monsoon season rolled its way around to Dryer Towers** that someone thought: 'Hang on a minute - the old hand drier was far less exciting and high tech, but at least it could deal with waterlogged socks.'
And, in a really obscure and slightly convoluted fashion,*** health is kind of like that, in that you don't notice what you've got til it's gone - but even then, sometimes it can take a surprisingly long time to catch your attention. I went from someone who never, ever had a headache to someone who got them regularly, but the change was so insidious over several years that it never even occurred to me that maybe I should mention this to a doctor - even after my heart had made it blindingly obvious to all and sundry that there was Something Clearly Wrong. Yes, I am just smart that way.
Now, I find myself (thank everything) on the flip side of that because I am (thank everything again) currently slowly getting better. Yes, I'm still not quite right, my hair's still falling out and my heart gave a very brief but exciting display of acrobatics as I ate my pasta last night,**** but I am so much better than I was. And I'm still in that happy honeymoon zone of improved health, where every now and again I have to take a moment to appreciate the fact that I can run for a bus without hyperventilating, that I can dance for an hour without needing a sit-down, and that my bruising has improved to the point where most days I can wear a skirt with no tights and not look like a victim of domestic violence.
Obviously the hope that I'm hoping ever so fervently is that I'm fixed and will continue to be fixed and, bar the odd MRI and pituitary-adenoma-related chat (for old times sake) I will darken my local hospital's doorstep much less frequently. I don't know if that will happen. But, although no doubt we'll all get used to the new hand dryer in time, I hope that - for as long as this improvement lasts - I don't lose my appreciation for feeling healthy :D
___________________________________________________________________________
* I say bathroom. I mean toilets. There is no bath in there. Because that would be weird.
**Just to clarify, I am making this up.
***Or, if you live in my head, a really obvious and straightforward one.
****Because the pasta was just that good. Incidentally, another side effect of this illness has been that I've completely lost all ability to appreciate lines in songs like "my heart skips a beat". I just hear them and think: Quick! To the cardiologist!
Monday, 7 November 2011
IMFW: Tom Thumb or Toe Thumb?
The Interesting Medical Fact of this Week is that a man who had his thumb sliced off has had his big toe sewn on to replace it. You might think that this would look roaringly obvious, but interestingly enough there is in fact a medical condition called clubbed thumb, which results in a thumb that looks a bit like a toe. And is consequently commonly known as toe thumb.* Don't believe me? It's on Wikipedia, so it must be true.
Rather hearteningly, Megan Fox keeps the hand models of this world out of penury by suffering from toe thumb herself.
_______________________________________________________________________
*Also as murderers thumb, but let's not cast nasturtiums.
Rather hearteningly, Megan Fox keeps the hand models of this world out of penury by suffering from toe thumb herself.
_______________________________________________________________________
*Also as murderers thumb, but let's not cast nasturtiums.
Monday, 31 October 2011
IMFW: Hedgehogs
Given the runaway success of my previous post about British spies wanting to sneak hormones into Hitler's food,* I have decided to attempt a regular weekly post about interesting medical or medicine-related facts. I have, you'll be pleased to know, imaginatively decided to call this series the Interesting Medical Fact of the Week, or IMFW for short.
Anyone who knows me well can tell you that I love hedgehogs greatly, and if I actually owned a house and could look after it properly, I would have one of my very own. It occurs to me that responsible pet ownership is probably one of the dread Seven Signs of Adulthood; when I was little, I would have happily housed a pony in the bathroom - if only my parents had bought me one. Damn them.
Anyway, as it turns out, I'm not just rambling incoherently about hedgehogs for no reason! Because the topic of this week's IMFW is the sonic hedgehog gene, a.k.a. SHH. If you ever want to send it mail, you can find it at chromosome 7, where it snuffles around in bars and punches anyone who calls it a rat.
I first heard of the sonic hedgehog gene in my first year at university, from friends who were studying medicine, and (not unreasonably) I initially believed that they were pulling my leg about its name. As it turns out, I should have had more faith in the doctors of the future. Its name originates from the fact that, when researchers created fruit fly embryos which lacked this and other similar genes, the embryos grew spiny protuberances. Apparently, researchers are always doing this kind of thing to fruit flies. Not out of scientific interest, you understand - they're just sick in the head.**
The sonic hedgehog gene (and its woodland genetics counterparts, the indian hedgehog gene and desert hedgehog gene) are cunning beasts, no doubt, but if you want a detailed description of what they do then you can head to wikipedia. Or simply grab a first year medical student and shake them repeatedly. Essentially, SHH is important in the development of embryos, as it codes for a protein which helps to signal the layout of bodyparts.
What I find particularly interesting is the debate around its name; a couple of years ago I listened to an interesting program on Radio 4*** which looked at the naming conventions in genetics, and lighted on the sonic hedgehog gene as a particularly good example of the fact that a name bestowed on a gene in the lab might seem hilarious in the light of certain spiny protuberances, but will sound rather less funny to the parents being told that their child has a serious disability because of a mutation in his or her sonic hedgehog gene.
_______________________________________________________________________
*Yes, you heard me - a whopping seven or so people read it. Crikey.
**Like me! :D
***Old before my time? Moi?
Anyone who knows me well can tell you that I love hedgehogs greatly, and if I actually owned a house and could look after it properly, I would have one of my very own. It occurs to me that responsible pet ownership is probably one of the dread Seven Signs of Adulthood; when I was little, I would have happily housed a pony in the bathroom - if only my parents had bought me one. Damn them.
Anyway, as it turns out, I'm not just rambling incoherently about hedgehogs for no reason! Because the topic of this week's IMFW is the sonic hedgehog gene, a.k.a. SHH. If you ever want to send it mail, you can find it at chromosome 7, where it snuffles around in bars and punches anyone who calls it a rat.
I first heard of the sonic hedgehog gene in my first year at university, from friends who were studying medicine, and (not unreasonably) I initially believed that they were pulling my leg about its name. As it turns out, I should have had more faith in the doctors of the future. Its name originates from the fact that, when researchers created fruit fly embryos which lacked this and other similar genes, the embryos grew spiny protuberances. Apparently, researchers are always doing this kind of thing to fruit flies. Not out of scientific interest, you understand - they're just sick in the head.**
The sonic hedgehog gene (and its woodland genetics counterparts, the indian hedgehog gene and desert hedgehog gene) are cunning beasts, no doubt, but if you want a detailed description of what they do then you can head to wikipedia. Or simply grab a first year medical student and shake them repeatedly. Essentially, SHH is important in the development of embryos, as it codes for a protein which helps to signal the layout of bodyparts.
What I find particularly interesting is the debate around its name; a couple of years ago I listened to an interesting program on Radio 4*** which looked at the naming conventions in genetics, and lighted on the sonic hedgehog gene as a particularly good example of the fact that a name bestowed on a gene in the lab might seem hilarious in the light of certain spiny protuberances, but will sound rather less funny to the parents being told that their child has a serious disability because of a mutation in his or her sonic hedgehog gene.
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| A hedgehog, though not an obviously sonic one. |
*Yes, you heard me - a whopping seven or so people read it. Crikey.
**Like me! :D
***Old before my time? Moi?
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